Nanomedicine for Gene and Drug Delivery
The development of nano-scaled carriers as gene and drug delivery platform has made a tremendous progress in the fight against cancer. Despite the progress, drug resistance and metastasis remain major challenges of nanotechnology-based cancer therapeutics. Our research aims to develop smart nano-scale carriers that can enhance the therapeutic efficacy with minimal side effects against recalcitrant drug-resistant and metastatic cancer types.
To achieve these goals, we use biocompatible and biodegradable polymeric and hybrid materials for targeted and controlled gene and drug delivery. We employ rational design principles for multi-functional nano-scaled vehicles with active targeting and stimulus-response mechanisms to increase the specificity and efficacy of the delivery systems. We currently focus on developing nanoparticle-based delivery systems for combination therapy using complementary and synergistic molecules for gene and chemotherapy. Our current efforts in this area can be found in Publications.
To achieve these goals, we use biocompatible and biodegradable polymeric and hybrid materials for targeted and controlled gene and drug delivery. We employ rational design principles for multi-functional nano-scaled vehicles with active targeting and stimulus-response mechanisms to increase the specificity and efficacy of the delivery systems. We currently focus on developing nanoparticle-based delivery systems for combination therapy using complementary and synergistic molecules for gene and chemotherapy. Our current efforts in this area can be found in Publications.